Genetics Punnett Square Lab

Choose the parents, and the Punnett square shows every possible child. Try one-gene and two-gene crosses, ABO blood groups and sex-linked conditions, then make real offspring at random to see how chance works.

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Words to know

Gene and alleleA gene is a section of DNA that controls a trait. An allele is one version of a gene, such as T (tall) or t (short).
Dominant / recessiveA dominant allele (capital letter) shows even when only one copy is present. A recessive allele (small letter) shows only when two copies are present.
GenotypeThe alleles an organism has, written as letters: TT, Tt or tt.
PhenotypeWhat you can see: tall or short.
Homozygous / heterozygousHomozygous means two identical alleles (TT or tt). Heterozygous means two different alleles (Tt). A heterozygous person who does not show a recessive condition is a carrier.
GameteA sex cell (sperm or egg). It has only one allele of each gene, so a Tt parent makes half T gametes and half t gametes.
Incomplete dominanceThe heterozygote is in between (red x white snapdragon gives pink).
CodominanceBoth alleles show fully in the heterozygote (roan cattle, blood group AB).

Mendel's classic ratios

CrossOffspring phenotypesName
TT x ttAll tall (all Tt)First generation (F1)
Tt x Tt3 tall : 1 shortSecond generation (F2), monohybrid ratio
Tt x tt1 tall : 1 shortTest cross (shows if a tall plant is TT or Tt)
RrYy x RrYy9 : 3 : 3 : 1Dihybrid ratio (law of independent assortment)
RW x RW (incomplete dominance)1 red : 2 pink : 1 white1 : 2 : 1

Practise what you learned

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Punnett squares give probabilities, not guarantees: each child is an independent chance event. Real families are small, so the ratios are only approximate. Works offline: after your first visit the lab is saved in your browser.

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